Innovative Solutions

The datasheet integrated in Ikaros and Isis can be used to generate customized print forms and reports.

mFISH: The single color gallery in Isis displays each single color channel, the fluorochrome profiles, and the DAPI image side by side.

With the relocation system ReloSys metaphases and other objects detected by a Metafer system can be analyzed remotely.

Metaphases on clonal slides are automatically assigned to the respective clones. The clone identifier is transferred to Ikaros after AutoCapt image acquisition.

With the extraordinary LED microscope illumination device high-quality color images in Brightfield are generated.

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Metafer: Versatile Imaging Automation Platform	Automation of image analysis is the core skill of MetaSystems. Based on the versatile high-throughput slide scanning platform Metafer a wide range of applications can be fully or partly automated. Metafer is used in cytogenetics, haematology, pathology, toxicology, mutation research, radiation biology, forensic sciences, and many other fields.
24/7 Image Server	Its robust architecture allows for using Metafer as a fully independent image server, which runs 24 hours a day, and 7 days a week. Images of reproducibly high quality are thus produced and shared within the workstation network, ready for analysis even while the next slides are still scanned.
Many Options and Upgrades	Like any MetaSystems product Metafer is an open system, offering many software packages and hardware options to cover a wide range of applications. Metafer is ready for use in GLP labs, and has an option for high security user administration. It can be extended with the 80-slides SlideFeeder, a robotic exchanger of slide trays, holding 8 slides each. Of course there are also a barcode option and an automated immersion oil dispenser available.
Last update: Friday, 22 January 2010 MSearch The fast MSearch metaphase finding software, running on the versatile scanning hardware platform Metafer, helps to vastly increase the throughput in routine and research laboratories. Unattended overnight scanning saves valuable daytime for the actual analysis. The superior performance of the system is based on a unique concept bringing together high quality hardware with innovative software algorithms. Read more... Last update: Thursday, 07 January 2010 MetaCyte MetaCyte, a software upgrade for the versatile slide scanning platform Metafer, excels with an unrivaled image quality and fully automated image enhancement. Additionally, it provides a tool kit of more than 250 analysis algorithms, thus being the perfect device for unattended routine image analysis. Read more... Last update: Tuesday, 03 November 2009 RCDetect Speed at highest accuracy is the secret of RCDetect, the rare cell detection system based on the versatile slide scanning platform Metafer. RCDetect with its unique detection algorithms and the special hardware setup scans up to 7,000 cells per second for the presence of rare events, for isolated tumor cells in blood or bone marrow preparations. Read more... Last update: Tuesday, 03 November 2009 AutoCapt The automated image acquisition software AutoCapt acquires high resolution images from metaphases detected by MSearch, either in Brightfield or also with fluorescent labels. It also can be used to acquire images from any other object detected by any other Metafer software. AutoCapt uses the position list generated by MSearch to relocate the metaphases, automatically centres and focusses the images before capturing, and captures images in up to 12 color channels and in different focus planes. Read more... Last update: Thursday, 12 November 2009 SlideFeeder MetaSystems provides the ingenious 80-slides SlideFeeder, which was especially designed and built for the use with Metafer systems. The feeder exchanges trays of 8 slides each, thus, reducing the time needed for the loading procedure. Read more... Last update: Monday, 14 December 2009 MNScore Metafer MNScore is the fast approach to analysis automation of the cytokinesis-block micronucleus assay. Being an add-on for the versatile slide scanning platform Metafer, MicroNuclei automatically detect bi-nucleated cells, and counts micronuclei. Read more... Last update: Tuesday, 03 November 2009 CometScan Fully automated and unattended analysis of single cell gel electrophoresis samples is a matter of routine for Metafer CometScan. Cells are automatically detected and selected based on well defined parameters. Read more... Last update: Tuesday, 03 November 2009 DCScore The DCScore software upgrade for Metafer automatically screens images previously captured with AutoCapt for the presence of dicentric chromosomes. Dicentrics are detected based on customizable parameters, are automatically counted, and are displayed in the result gallery for inspection. Read more... Last update: Friday, 22 January 2010 ReloSys Whatever type of object you want to relocate remotely, ReloSys does this job fast and reliably. Transfer your slide from the scanning system Metafer to a ReloSys station and relocate metaphases, cells, or other objects in less than a second for the analysis of chromosomes, micronuclei or interphase FISH signals. And since ReloSys is a remote relocation system, it can already be used while Metafer is still going on with scanning - thus providing an enourmous increase in image analysis throughput. Read more... Last update: Wednesday, 14 July 2010 VSlide Large tissue sections or TMA fields can be automatically transferred to a high resolution overview image with Metafer VSlide. VSlide generates highest quality images either in Brightfield or fluorescence. Read more...

Ikaros and Isis	MetaSystems offers a wide range of solutions for automated karyotyping and fluorescence imaging. Common basis are the two main systems Ikaros (karyotyping) and Isis (fluorescence imaging), which are both available in many different configurations.
Powerful Image Enhancement	Both systems provide unique image acquisition, enhancement, and analysis tools, and due to their modular architecture they are well prepared to be used in a large workspace with multiple networked stations.
Easy Case and Image Data Management	Ikaros and Isis share the same case data management, and with the help of the convenient MetaServer and MetaClient data and image management it is easy to retrieve and analyze data and images system-wide and in real-time.
Last update: Tuesday, 10 November 2009 Ikaros The karyotyping system Ikaros combines an intuitive graphic user interface with a variety of powerful imaging tools. Ikaros has been developed with focus on security, speed, and ease of use. Designed to minimize the number of interactions, Ikaros ensures amazingly fast results and is recognized as the fastest system of its kind. Read more... Last update: Thursday, 05 November 2009 Isis Due to its user-friendly architecture the Isis fluorescence in situ imaging system lets even complex FISH analyses be easy and fast. High quality color images with up to 12 different fluorochromes are captured and processed easily, and in a reproducible and fully documented way. Read more... Last update: Tuesday, 29 June 2010 Isis - Color Karyotyping Software The Isis color karyotyping upgrade adds full Ikaros karyotyping functionality for fluorescence metaphases to any Isis system. Functions like object threshold settings, chromosome separation, chromosome assignment, and for chromosome comparison become conveniently accessible on a second command menu. A comprehensive set of predefined karyogram forms for different species and requirements is provided, additionally all forms are easy modifiable by the intuitive user interface. Any processing step can be undone, and various color display modes provide different views for reliable analysis. Read more... Last update: Monday, 26 October 2009 Isis - CGH Software Isis CGH software provides a versatile toolbox for analysis of comparative genomic hybridization (CGH) slides. Due to the sophisticated statistic approach deviations with sizes down to 3 mbp can be detected. Read more... Last update: Monday, 07 December 2009 Isis - Telomere Analysis Software Isis telomere analysis software provides a versatile toolbox for analysis of telomere ends. Many possibilities of displaying the results enhances the analysis. Read more... Last update: Monday, 23 November 2009 Isis - mFISH and mBAND Software Precise analysis of chromosomal rearrangements becomes easy with the multicolor FISH (mFISH) and multicolor chromosome banding (mBAND) software add-on for Isis. Read more... Last update: Thursday, 05 November 2009 MetaServer/ MetaClient MetaServer and MetaClient are the two components of a software bundle designed to maintain, organize, analyze, and summarize data produced by Ikaros and Isis. With MetaServer and MetaClient the user always has full insight into all images, cases, and patient data located in the network. Read more... Last update: Monday, 26 October 2009 MetaArchive MetaArchive, being a standard package installed on each first Ikaros or Isis system in the network, provides the most convenient and safest procedure for daily or weekly incremental archiving of images and case data. MetaArchive uses DVD-RAMs for data storage, which are known to be the most stable and long-lasting external storage media available. Read more...

High Quality and Ease of Use	MetaSystems DNA probe kits excel by their outstanding quality and stability. Many FISH users throughout the world appreciate the ease of use and the amazing hybridization results of any MetaSystems probe kit.
Wide Variety of Applications	The portfolio of MetaSystems probe kits covers whole chromosome paints (XCP), arm-specific chromosome paints (XCAP), multicolor FISH probe kits for humans (24Xyte), and mice (21XMouse), arm-specific mFISH kits for human (X^aCyte), multicolor fluorochrome banding kits (XCyte mBAND kits), and a range of locus-specific hematology probe kits (XL). Other products are in preparation.

Please refer to our DNA probe kits overview page for details.