MetaSystems International WebsiteThe datasheet integrated in Ikaros and Isis can be used to generate customized print forms and reports.
mFISH: The single color gallery in Isis displays each single color channel, the fluorochrome profiles, and the DAPI image side by side.
With the relocation system ReloSys metaphases and other objects detected by a Metafer system can be analyzed remotely.
Metaphases on clonal slides are automatically assigned to the respective clones. The clone identifier is transferred to Ikaros after AutoCapt image acquisition.
With the extraordinary LED microscope illumination device high-quality color images in Brightfield are generated.
With the tissue FISH module analysis of cell signals in tissues is very easy. Results are available immediately and can be easily validated.
Patient and image data can be conveniently displayed, filtered, and summarized.
DCScore
Automatic Scoring of Dicentric Chromosomes
The analysis of chromosomal aberrations is an established method to evaluate toxic effects on the genome caused by external influences, e.g. radiation, pollution, medication, and others. Dicentric chromosomes are here often used as leading type of aberrations. Especially when it comes to unpredicted events, for example accidents where unknown amounts of ionizing radiation were released, the chromosomal aberration test is of utmost importance to estimate the overall dose to which potential victims were exposed (biological dosimetry). Unfortunately the analysis of chromosomal rearrangements is time consuming and tedious, which is an obstacle in an emergency situation such as a radiation accident. The Metafer software upgrade DCScore is the perfect answer to this problem. DCScore is capable to automatically and unattended score dicentric chromosomes in a high throughput mode, and can even be applied by people who are relatively untrained in the analysis of chromosomal aberrations. DCScore is fast, and its usefulness for population triages has been proven to be equivalent to and as reliable as manual analyses.
DCScore uses the automatic capture module AutoCapt to acquire the metaphases that were detected by the MSearchmetaphase finder.