MetaSystems Announces the Launch of a New TissueFISH Module
Convenient analysis of cell signals in tissue sections with Metafer slide scanning platform
The analysis of FISH signals in cells which are part of a solid tissue section requires special tools and methods. Based on the requirements of users and researchers, MetaSystems has now launched a dedicated software module for automated analysis of signals in tissues. The module is based on the powerful analysis engine of MetaCyte, extended with a new, convenient analysis environment. The user interface supports either conventional mouse control or an optional interactive pen display.
After image acquisition with Metafer MetaCyte special algorithms automatically separate suitable cells. Additional cell selection is performed by the researcher, simply by encircling the respective object on screen and, thus, adding it to the list of objects to be analyzed. Analysis is started automatically for all marked cells or nuclei, and the results are immediately displayed on screen as gallery image, and are also summarized in a data histogram.
"The routine analysis of tissue samples requires dedicated software tools providing a convenient and intuitive workflow", MetaSystems officials stated on the occasion of the new product launch. "With the new TissueFISH module for Metafer we have created the optimal environment for this task. We are convinced that, with this new tool, even large studies can be analyzed reliably and comfortably."
The new TissueFISH module will be available for Metafer MetaCyte systems and for separate analysis stations.
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Metafer MNScore:
Micronuclei Analysis in Environmental Studies
"In conlusion, this work is the first human biomonitoring study focused on the measurement of MN by automated image analysis for assessing chromosomal damage as a result of environmental mutagen exposure. [...] Further, our findings indicate the ability of the automated system to easily analyze slides with a low density of cells that would be very laborious to score using visual analysis. [...] Furthermore, we suggest that the classifier setting used in this work be used in other biomonitoring studies to allow for comparable inter-laboratory results."
Cited from:
The impact of air pollution on the levels of micronuclei measured by automated image analysis.
A. Rossnerova et al., Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 669:2 (2009) Read more ...