Innovative Solutions

Because of mosaicism among embryonic cells it is usually required to analyze a relatively high number of amniotic cells in prenatal cytogenetic studies, thus increasing probability that metaphases from all clones are inspected. A common method to overcome this obstacle is the analysis of in-situ slides with various colonies (each representing a single clone). The automated metaphase finder Metafer MSearch includes the many tools to help for clone slide analysis.
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The cytokinesis-block micronucleus (CBMN) assay is widely used to test substances for their ability to cause DNA damage. Typically MNvit tests are used in the frame of biological dosimetry, toxicology, and environmental studies. The OECD recommends to also quantify the effect of cytotoxicity, i.e. the impact of the tested substance on cell proliferation. In the CBMN assay cytotoxicity is expressed by the Cytokinesis-Block Proliferation Index (CBPI) ...
Download flyer to learn more about CBPI measurement with Metafer.

With the unique combination of Metafer MetaCyte, the integrated tool for TMA analysis, and the VSlide digital slide imaging software, MetaSystems offers a complete package for precise and effortless, automated TMA analyses...

Download flyer to learn more about TMA analysis with Metafer.

The analysis of FISH signals in cell nuclei which are part of a solid tissue section requires special tools and methods. Based on the requirements of users and researchers, MetaSystems has now launched a dedicated software module for automated analysis of signals in tissues. The module is based on the powerful analysis engine of MetaCyte...
Download flyer to learn more about TissueFISH with Metafer.

The new Tissue Matching tools, which are included in the latest Metafer and MetaViewer versions, now allow for easy segmentation, alignment, and matching of serial sections from the same tissue block. The system automatically generates overview images of two subsequent sections, and a convenient tool offers functionality to check and, if required, interactively match the images to each other.
Download flyer to learn more about Tissue Matching with Metafer and MetaViewer.