Innovative Solutions

MetaSystems is proud to offer a wide range of high quality DNA probes known to reach a special standard in reliability of the results. Together with the unique combination of our expert-knowledge, customer-friendly support and the MetaSystems imaging systems which are in routine use throughout the world, we are ready to provide additional valuable benefits to each customer. The following pages are a complete catalogue of the MetaSystems probe kits portfolio. For easy access target chromosomes may be selected from the bar above. There are also icons for a detailed probes kit list, and a basic list view. Alternatively the probe kits family of interest can be selected from below.

	XL XCyting Locus-Specific Probe Kits Locus-specific probes provide precise and rapid data by detecting amplifications, deletions, or translocation of genes. MetaSystems offers an expanding range of high-quality XL locus-specific probes. Show XL Probe Kits List		XA XCyting AneuScore Probe Kits With XA AneuScore probe kits the detection of copy number variations of human chromosomes. Show XA Probe Kits List
	XCP XCyting Chromosome Paints Whole chromosome paints have become a valuable and widely used tool for identifying structural and numerical abnormalities, as well as cryptic abnormalities beyond the resolution of G-banding. Show XCP Probe Kits List		XCE XCyting Centromere Enumeration Probes XCE probes hybridize to human highly repetitive sequences (also called Satellite DNA) located at and around the centromeric region of chromosomes. Show XCE Probe Kits List
	XCyting Multicolor DNA Probe Kits The multicolor probe kits of MetaSystems allow for simultaneous analysis of all chromosomes in a metaphase (multicolor FISH / mFISH). Show Multicolor Probe Kits List

MetaSystems also offers chromosome paints for rat and mouse chromosomes, which are currently not published here. However, this page will be regularly updated, so please come back later. Meanwhile please contact This e-mail address is being protected from spambots. You need JavaScript enabled to view it   for details on unlisted probe kits.

Fluorescence in situ hybridization (FISH) has become a major tool for research in human chromosomes, tumor cytogenetics and diagnostics. Its is routinely applied in genetics and allows nearly unlimited and targeted visualization of genomic DNA using either metaphase spreads, interphase nuclei, tissue sections, or living cells. FISH applications are particularly important for the detection of structural rearrangements such as microdeletions, translocations, inversions, and insertions, as well as for identification of marker chromosomes, characterization of chromosome breakpoints, and prenatal aneuploidy testing. The clinical impact of FISH is huge especially in the diagnosis, prognosis and therapy of haematological diseases. Here, FISH plays a central role in combination with classic chromosome banding analysis to rapidly detect and to verify specific aberrations.