Innovative Solutions for Automated Imaging

MetaSystems has been developing and producing system software for automated microscopy since 1986. Today, users in more than 103 countries rely on the laboratory solutions by MetaSystems.

In addition to generating the highest quality images, our modern approaches include an advanced workflow management that grows with your requirements.

You would like to discover what others are accomplishing with their MetaSystems products? Read through the list of peer-reviewed publications from our customers!

If you do not find what you are looking for, please do not hesitate to contact the MetaSystems partner in your region.

Platelet Characteristics in Long--Covid Patients

Here we closely look at laboratory methods used to prepare samples to study platelets, and also investigate the use an automated method for unbiased morphological analysis using microscopy. [...] to further improve platelet analysis, here, we introduce an automated platelet analysis method using the MetaCyte Metafer classifier. [...] In the MetaCyte Metafer classifier analysis, we defined 14 discrete size ranges for platelet dimensions to accommodate varying conditions of platelet activation. [...] While fluorescence microscopy provides valuable insights into structure and morphology, questions often arise regarding the conditions under which the images were captured and analysed. Another important consideration is analyst bias, that is significantly influenced by the level of expertise of the analyst capturing microscopy images. [...] In conclusion, our findings indicate that the MetaCyte Metafer classifier delivers accurate, consistent, and unbiased results. The automated MetaCyte Metafer classifier system demonstrated significant utility in analyzing platelet activation across a wide range of size categories. [...] The precision in segmenting platelet size groups provides high-resolution insights into the progression of platelet activation, thereby highlighting subtle morphological changes that could be crucial in identifying and understanding thrombo-inflammatory conditions like Long COVID.

Cited From: Journal of thrombosis and thrombolysis (2025) Read more...
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