Digitization of large samples like tissue sections is made easy with Metafer VSlide. Highest flexibility allows to combine various magnifications, contrasting methods, and color display modes. Click the image for more information.
The karyotyping system Ikaros combines an intuitive graphic user interface with a variety of powerful tools to provide highest flexibility and ease of use. Ikaros has been developed with focus on security, speed, and quality.
Isis is the professional tool for fluorescence imaging. Images with up to 12 color channels are easily captured, and many tools are provided for enhancing and analyzing images. Upgrades for mFISH, mBAND, CGH, and telomere analysis are availalable.
Automated detection of metaphases, fast, easy, and reliable: Metafer MSearch is the ideal tool for any assay where rapid detection and sorting of metaphases are required.
MetaCyte is an extremely versatile slide scanning system, which uses up to 250 feature algorithms to obtain highest quality images in transmitted light or Brightfield.
The wide range of MetaSystems DNA probe kits includes chromosome paints for human, mice, CHO, and rat, multicolor FISH probe kits, multicolor chromosome banding kits (mBAND), and locus specific probe kits. Klick the image to access the probes catalogue.
The SlideFeeder x80 is the ideal add-on for any Metafer slide scanning system. With the SlideFeeder the capacity of Metafer is increased, and large experiments can be scanned completely unattended. Click the image for more details.
With the comprehensive MetaServer / MetaClient software bundle patient and image data is organized in a very flexible and convenient way. Reporting, statistics, and archiving of cases are only a matter of a few clicks. Click the image for more details.
With offices in Germany, Hong Kong, Bangalore, and Boston, and with a wide network of partners in many other countries, MetaSystems serves a global market with professional imaging systems. Click the image to find MetaSytems partners in your region.
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Automated Scoring of Radiation-Induced gamma-H2AX Foci
"For automated slide scanning and foci scoring, the MetaCyte software module of the Metafer 4 scanning system [...] was used. [...] To validate the automated foci scoring, the combined images stored in the image gallery, were manually analyzed by 2 independent scorers. [...] The automated processing of the slides offers both objectivity in scoring and increased statistical power [...]. All our results are based on automated scoring of foci number using MetaCyte software. Preliminary validation of this automated system by comparison with manual foci analysis demonstrated the suitability of the automated scoring mode."
Early increase of radiation-induced [gamma]H2AX foci in a human Ku70/80 knockdown cell line characterized by an enhanced radiosensitivity.
Veerle Vandersickel et al., J. Radiat. Res. 51 (2010) Read more ...