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The datasheet integrated in Ikaros and Isis can be used to generate customized print forms and reports.

mFISH: The single color gallery in Isis displays each single color channel, the fluorochrome profiles, and the DAPI image side by side.

With the relocation system ReloSys metaphases and other objects detected by a Metafer system can be analyzed remotely.

Metaphases on clonal slides are automatically assigned to the respective clones. The clone identifier is transferred to Ikaros after AutoCapt image acquisition.

With the extraordinary LED microscope illumination device high-quality color images in Brightfield are generated.

With the tissue FISH module analysis of cell signals in tissues is very easy. Results are available immediately and can be easily validated.

Patient and image data can be conveniently displayed, filtered, and summarized.

MetaSystems Product Overview


Metafer: Versatile
Imaging Automation Platform

Automation of image analysis is the core skill of MetaSystems. Based on the versatile high-throughput slide scanning platform Metafer a wide range of applications can be fully or partly automated. Metafer is used in cytogenetics, hematology, pathology, toxicology, mutation research, radiation biology, forensic sciences, and many other fields.

24/7 Image Server

Its robust architecture allows for using Metafer as a fully independent image server, which runs 24 hours a day, and 7 days a week. Images of reproducibly high quality are thus produced and shared within the workstation network, ready for analysis even while the next slides are still scanned.

Many Options and Upgrades

Like any MetaSystems product Metafer is an open system, offering many software packages and hardware options to cover a wide range of applications. Metafer is ready for use in GLP labs, and has an option for high security user administration. It can be extended with the 880-slides SlideFeeder*, a robotic exchanger of slide trays, holding 5 slides each. Of course there are also a barcode option and an automated immersion oil dispenser available.

  • Last update: Tuesday, 25 November 2014
Tissue FISH
The analysis of FISH signals in cells which are part of a solid tissue section requires special tools and methods. Based on the requirements of users and researchers, MetaSystems has now launched a dedicated software module for automated analysis of signals in tissues. The module is based on the powerful analysis engine of MetaCyte.
  • Last update: Tuesday, 07 May 2013
The fast MSearch metaphase finding software, running on the versatile scanning hardware platform Metafer, helps to vastly increase the throughput in routine and research laboratories. Unattended overnight scanning saves valuable daytime for the actual analysis. The superior performance of the system is based on a unique concept bringing together...
  • Last update: Wednesday, 18 September 2013
MetaCyte, a software upgrade for the versatile slide scanning platform Metafer, excels with an unrivaled image quality and fully automated image enhancement. Additionally, it provides a tool kit of more than 250 imaging algorithms, thus being the perfect device for unattended routine imaging.
  • Last update: Wednesday, 07 May 2014
Advances in computer and software technology have opened new opportunities of slide analysis in pathology. Today it is possible to completely digitize slides, and to analyze them 'offline' on any computer monitor – even through the net. VSlide automatically generates high quality digital slides with focus stacks, unlimited color channels,...
  • Last update: Monday, 29 April 2013
The automated image acquisition software AutoCapt acquires high resolution images from metaphases detected by MSearch, either in Brightfield or also with fluorescent labels. It also can be used to acquire images from any other object detected by any other Metafer software. AutoCapt uses the position list generated by MSearch to relocate...
  • Last update: Thursday, 27 February 2014
SlideFeeder x80
A meaningful extension of any Metafer system is the ingenious new SlideFeeder x80 with a capacity of up to 880 slides. Slides are stored in handy frame magazines, which can be exchanged even while Metafer is scanning. This makes the system the ideal 24/7 image server.
  • Last update: Wednesday, 08 February 2012
Metafer MNScore is the fast approach to analysis automation of the cytokinesis-block micronucleus assay. Being an add-on for the versatile slide scanning platform Metafer, MNScore automatically detect bi-nucleated cells, and counts micronuclei.
  • Last update: Thursday, 29 March 2012
Fully automated and unattended analysis of single cell gel electrophoresis samples is a matter of routine for Metafer CometScan. Cells are automatically detected and selected based on well defined parameters.
  • Last update: Tuesday, 03 November 2009
The DCScore software upgrade for Metafer automatically screens images previously captured with AutoCapt for the presence of dicentric chromosomes. Dicentrics are detected based on customizable parameters, are automatically counted, and are displayed in the result gallery for inspection.
  • Last update: Monday, 29 April 2013
Speed at highest accuracy is the secret of RCDetect, the rare cell detection system based on the versatile slide scanning platform Metafer. RCDetect with its unique detection algorithms and the special hardware setup scans up to 7,000 cells per second for the presence of rare events, for isolated tumor cells in blood or bone marrow preparations.
  • Last update: Monday, 29 April 2013
Whatever type of object you want to relocate remotely, ReloSys does this job fast and reliably. Transfer your slide from the scanning system Metafer to a ReloSys station and relocate metaphases, cells, or other objects in less than a second for the analysis of chromosomes, micronuclei or interphase FISH signals. And since ReloSys is...


Ikaros and Isis

MetaSystems offers a wide range of solutions for automated karyotyping and fluorescence imaging. Common basis are the two main systems Ikaros (karyotyping) and Isis (fluorescence imaging), which are both available in many different configurations.

Powerful Image Enhancement

Both systems provide unique image acquisition, enhancement, and analysis tools, and due to their modular architecture they are well prepared to be used in a large workspace with multiple networked stations.

Easy Case and
Image Data Management

Ikaros and Isis share the same case data management, and with the help of the convenient MetaServer and MetaClient data and image management it is easy to retrieve and analyze data and images system-wide and in real-time.


  • Last update: Friday, 16 November 2012
The karyotyping system Ikaros combines an intuitive graphic user interface with a variety of powerful imaging tools. Ikaros has been developed with focus on security, speed, and ease of use. Designed to minimize the number of interactions, Ikaros ensures amazingly fast results and is recognized as the fastest system...
  • Last update: Wednesday, 20 August 2014
Due to its user-friendly architecture the Isis fluorescence in situ imaging system lets even complex FISH imaging tasks be easy and fast. High quality color images with up to 12 different fluorochromes are captured and processed easily, and in a reproducible and fully documented way.
  • Last update: Wednesday, 20 August 2014
Isis - Color Karyotyping Software
The Isis color karyotyping upgrade adds full Ikaros karyotyping functionality for fluorescence metaphases to any Isis system. A comprehensive set of predefined karyogram forms for different species and requirements is provided, additionally all forms are easy modifiable by the intuitive user interface. Any processing...
  • Last update: Monday, 29 April 2013
Isis - CGH Software
Isis CGH software provides a versatile toolbox for analysis of comparative genomic hybridization (CGH) slides. Due to the sophisticated statistic approach deviations with sizes down to 3 mbp can be detected.
  • Last update: Monday, 29 April 2013
Isis - Telomere Analysis Software
Isis telomere analysis software provides a versatile toolbox for analysis of telomere ends. Many possibilities of displaying the results enhances the analysis.
  • Last update: Monday, 29 April 2013
Isis - mFISH and mBAND Software
Precise analysis of chromosomal rearrangements becomes easy with the multicolor FISH (mFISH) and multicolor chromosome banding (mBAND) software add-on for Isis. 
  • Last update: Wednesday, 05 March 2014
MetaServer/ MetaClient
MetaServer and MetaClient are the two components of a software bundle designed to maintain, organize, analyze, and summarize data produced by Ikaros, Isis, and the VSlide virtual slide system. With MetaServer and MetaClient the user gets a convenient overview of all images, cases, and patient data located in the...
  • Last update: Monday, 29 April 2013
MetaArchive, being a standard package installed on each first Ikaros or Isis system in the network, provides the most convenient and safest procedure for daily or weekly incremental archiving of images and case data. MetaArchive uses RDX drives for data storage, which are known to be the most stable and...


High Quality and Ease of Use

MetaSystems DNA probe kits excel by their outstanding quality and stability. Many FISH users throughout the world appreciate the ease of use and the amazing hybridization results of any MetaSystems probe kit.

Wide Variety of Applications

The portfolio of MetaSystems probe kits covers whole chromosome paints (XCP), arm-specific chromosome paints (XCAP), multicolor FISH probe kits for humans (24Xyte), and mice (21XMouse), arm-specific mFISH kits for human (XaCyte), multicolor fluorochrome banding kits (XCyte mBAND kits), and a range of locus-specific hematology probe kits (XL). Other products are in preparation.

Please refer to our DNA probe kits main page for details.